A temperature-based diagnostic approach for paper-based microfluidics |
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| Authors: | A Terzis " target="_blank">G Yang I Zarikos E Elizalde B Weigand A Kalfas X Ding |
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| Affiliation: | 1.Institute of Aerospace Thermodynamics (ITLR),University of Stuttgart,Stuttgart,Germany;2.Environmental Hydrogeology Group, Department of Earth Sciences,University of Utrecht,Utrecht,The Netherlands;3.Laboratorio de Fluidodinámica, Facultad de Ingeniería UBA,CONICET,Buenos Aires,Argentina;4.School of Engineering,Aristotle University of Thessaloniki,Thessaloníki,Greece;5.Institute for Personalised Medicine, School of Biomedical Engineering,Shanghai Jiao Tong University,Shanghai,China |
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| Abstract: | We present the potential of a quantitative temperature-based diagnostic approach for paper-based microfluidics, extending the work of Terzis et al. (J Colloid Interface Sci 504:751–757, 2017) which demonstrated a significant heat release at the liquid front during capillary-driven flows in cellulosic materials. Here, we investigate the applicability of biological fluids to provide a temperature rise at the imbibition front, and successfully demonstrate a monotonic trend between the level of local temperature rise and the concentration of specific analytes. In addition, effects of paper thickness and width are also examined. |
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