基于固相萃取-液相色谱-串联质谱法的纺织品中三氯生和三氯卡班的测定

采用固相萃取-液相色谱-串联质谱技术(SPE-LC-MS/MS)建立了同时测定纺织品中三氯生和三氯卡班的分析方法。样品用二氯甲烷超声提取，C18固相萃取净化后分析。串联质谱在多反应监测(MRM)模式下检测目标分析物，以保留时间和特征离子对(母离子和碎片离子)信息比较进行定性和定量分析。三氯生和三氯卡班的线性范围分别为1.0~50.0 ng/mL、0.25~50.0 ng/mL。方法的定量限为1.0和0.25 μg/kg，平均回收率为84.5% ~ 108.2 %，相对标准偏差小于8.1 %。实验结果表明该方法准确、灵敏，可用于纺织品中三氯生和三氯卡班的分析测定。

Determination of triclosan and triclocarban in textiles by solid-phase extraction and liquid chromatography wave-mass spectrometry tandem

A method for the determination of triclosan and triclocarban in textiles was developed by solid phase extraction and liquid chromatography-tandemed mass spectrometry (SPE-LC-MS/MS). The sample was extracted with dichloromethane by ultrasonic and clean-up on a C18 SPE cartridge. The analyte was determined by an electrospray ionization tandem mass spectrometry in multiple reactions monitoring (MRMs) mode. The qualitative and quantitative analyses was based on the retention times and characteristic ion pairs consisting of one parent ion and fragment ions of the analyte. Linearities in the range of 1.0~50.0 ng/mL and 0.25~50.0 ng/mL for triclosan and triclocarban, respectively. The limits of quantification (LOQs) for triclosan and triclocarban were 1.0 and 0.25 μg/kg, respectively, the average recoveries were in the range of 84.5% ~ 108.2 % with the relative standard deviations below 8.1 %. This method is accurate and sensitive, and it is suitable for the analysis of triclosan and triclocarban in textiles.