Vertebrate segmentation: the clock is linked to Notch signalling |
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Authors: | YJ Jiang L Smithers J Lewis |
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Affiliation: | Vertebrate Development Laboratory Imperial Cancer Research Fund 44 Lincoln's Inn Fields London WC2A 3PX UK. |
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Abstract: | The periodic formation of somites during vertebrate segmentation has been suggested to involve a molecular 'segmentation clock'. Recent observations of cyclic Lunatic fringe expression in chick and mouse embryos link the segmentation clock to Delta-Notch signalling. |
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