An Overview of Synergistic Data Tools for Biological Scrutiny |
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| Authors: | Tsviya Olender Marilyn Safran Ron Edgar Gil Stelzer Noam Nativ Naomi Rosen Ronit Shtrichman Yaron Mazor Michael D West Ifat Keydar Noa Rappaport Frida Belinky David Warshawsky Doron Lancet |
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| Affiliation: | 1. Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100 (Israel);2. LifeMap Sciences, HaNehoshet 10, Tel Aviv 69710 (Israel) |
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| Abstract: | A network of biological databases is reviewed, supplying a framework for studies of human genes and the association of their genomic variations with human phenotypes. The network is composed of GeneCards, the human gene compendium, which provides comprehensive information on all known and predicted human genes, along with its suite members GeneDecks and GeneLoc. Two databases are shown that address genes and variations focusing on olfactory reception (HORDE) and transduction (GOSdb). In the realm of disease scrutiny, we portray MalaCards, a novel comprehensive database of human diseases and their annotations. Also shown is GeneKid, a tool aimed at generating novel kidney disease biomarkers using systems biology, as well as Xome, a database for whole-exome next-generation DNA sequences for human diseases in the Israeli population. Finally, we show LifeMap Discovery, a database of embryonic development, stem cell research and regenerative medicine, which links to both GeneCards and MalaCards. |
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| Keywords: | bioinformatics databases gene sequencing genetic disease olfaction |
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