In vitro study of platelet adhesion on medical nickel-free stainless steel surface |
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| Affiliation: | 1. Larionov’s Institute of Pysical-Technical Problems of the North SB RAS, 1 Oktyabrskaja str., 677891, Yakutsk, Russia;2. Academy of Science of Republic of Sakha (Yakutia), 33 Lenina av., 677007, Yakutsk, Russia;3. Ammosov’s North Eastern Federal University, 33 Belinskogo str., 677891, Yakutsk, Russia;1. Unit of Urology/Division of Oncology, IRCCS Ospedale San Raffaele, URI Milan, Italy;2. Department of Urology, Mayo Clinic, Rochester, MN;3. Department of Urology, Magna Graecia University of Catanzaro, Doctorate Research Program, Catanzaro, Italy;4. Department of Urology, University of Bologna, S. Orsola-Malpighi Hospital, Bologna, Italy;5. Department of Urology, Medical University of Vienna, Vienna, Austria |
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| Abstract: | A new nickel-free austenitic stainless steel, named BIOSSN4, has been recently developed to avoid the sensitivity to Ni ions. In the present study, the blood compatibility of the nickel-free stainless steel was evaluated in vitro by the platelet-rich plasma adhesion test with comparison to 316L stainless steel. The result shows that the nickel-free stainless steel only causes less activation of platelets, which was indicated by their morphology and low spreading. The result suggests that the nickel-free stainless steel should have better blood compatibility compared with 316L stainless steel and, as a bio-material, it should have obvious advantage and potential applications. |
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