| 不同魔芋葡甘聚糖降解物抑制肿瘤活性的比较研究 |
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| 引用本文： | 王志江,李致瑜,黄水华,姚闽娜.不同魔芋葡甘聚糖降解物抑制肿瘤活性的比较研究[J].食品与机械,2011,27(5). |
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| 作者姓名： | 王志江 李致瑜 黄水华 姚闽娜 |
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| 作者单位： | 福建农林大学食品科学学院,福建福州,350002 |
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| 基金项目： | 国家大学生创新性实验计划项目(编号:101038923); 福建省自然科学基金资助项目(编号:2011J01285); 国家自然科学基金项目(编号:31071518) |
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| 摘 要： | 为了进一步明确不同品种魔芋抗肿瘤活性的差异,分别以白魔芋和花魔芋为原料,先对其所含的魔芋葡甘聚糖(KGM)进行辐照酶解处理制备魔芋葡甘聚糖片段(KF),再通过体内外抑瘤试验,分别探究两种降解产物的抗肿瘤活性,并作分析比较。结果表明:两个品种的魔芋葡甘聚糖片段浓度的增加,宫颈癌细胞株的存活率逐渐降低,艾氏腹水瘤(EAC)小鼠的移植性实体瘤和脏器指数均有不同程度的增强;白魔芋葡甘聚糖片段的抑制肿瘤活性比花魔芋葡甘聚糖片段的强。
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| 关 键 词： | 魔芋葡甘聚糖 降解 抑制肿瘤 活性 |
Comparative studies of antitumor activities of Konjac glucomannan degradation products |
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| WANG Zhi-jiang,LI Zhi-yu,HUANG Shui-hua,YAO Min-na.Comparative studies of antitumor activities of Konjac glucomannan degradation products[J].Food and Machinery,2011,27(5). |
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| Authors: | WANG Zhi-jiang LI Zhi-yu HUANG Shui-hua YAO Min-na |
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| Affiliation: | WANG Zhi-jiang LI Zhi-yu HUANG Shui-hua YAO Min-na(College of Food Science,Fujian Agriculture and Forestry University,Fuzhou,Fujian350002,China) |
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| Abstract: | This paper further clarifies the antitumor activity differ-ences between White Konjac glucomannan(KGM)and Spend konjac glucomannan.Firstly,had irradiation enzyme treatment to KGM to get segments of Konjac glucomannan(KF).Then,compare the anti-tumor activities with tumor suppression experiment in vivo and in vitro.The results were as follows:the liability of Hela cells de-creased with the increase of the concentration of two KGM.Portabil-ity solid tumor and viscera exponents of Adenauer ascites tumor(EAC)mou... |
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| Keywords: | Konjac glucomannan degradation inhibit tumor activity |
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