| 胰腺炎发病机制相关信号通路研究进展 |
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| 引用本文： | 黄会珍,韩磊,林晓冬,陈磊.胰腺炎发病机制相关信号通路研究进展[J].金属学报,2023,28(1):109-113. |
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| 作者姓名： | 黄会珍 韩磊 林晓冬 陈磊 |
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| 作者单位： | 山东省药学科学院 山东省生物药物重点实验室，济南 250101，山东 |
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| 基金项目： | 山东省重大创新工程（2021ZDSYS07） |
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| 摘 要： | 胰腺炎是一种常见的消化性疾病，临床症状主要有腹部疼痛、消瘦、腹泻、脂肪泻等。迄今为止胰腺炎的发病机制尚未阐明，且对此靶标明确、疗效稳定、副作用小的药物寥寥无几。本文对胰腺炎的可能发病机制相关的信号通路及其相关的治疗方法进行总结叙述，以期为治疗胰腺炎的新药研究提供新的思路与参考。
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| 关 键 词： | 胰腺炎 发病机制 信号通路 |
| 收稿时间： | 2022-08-16 |
| 修稿时间： | 2022-12-15 |
Research progress on signal pathways related to the pathogenesis of pancreatitis |
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| HUANG Huizhen,HAN Lei,LIN Xiaodong,CHEN Lei.Research progress on signal pathways related to the pathogenesis of pancreatitis[J].Acta Metallurgica Sinica,2023,28(1):109-113. |
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| Authors: | HUANG Huizhen HAN Lei LIN Xiaodong CHEN Lei |
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| Affiliation: | Shandong Academy of Pharmaceutical Sciences, Shandong Provincial Laboratory of Biological Drugs, Jinan 250101, Shandong, China |
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| Abstract: | Pancreatitis is a common digestive disease, the main clinical symptoms are abdominal pain, emaciation, diarrhea, fatty diarrhea and so on. So far, the pathogenesis of pancreatitis has not been clarified, and there are few drugs with clear target, stable curative effect and fewer side effects. This paper summarizes the possible related signal pathways and related treatment methods of pathogenesis of pancreatitis, in order to provide new ideas and references for the research of new drugs for the treatment of pancreatitis. |
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| Keywords: | pancreatitis pathogenesis signal pathway |
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