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Caveolae and Caveolin-1 Integrate Reverse Cholesterol Transport and Inflammation in Atherosclerosis |
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| Authors: | Li Qin Neng Zhu Bao-Xue Ao Chan Liu Ya-Ning Shi Ke Du Jian-Xiong Chen Xi-Long Zheng Duan-Fang Liao |
| Abstract: | Lipid disorder and inflammation play critical roles in the development of atherosclerosis. Reverse cholesterol transport is a key event in lipid metabolism. Caveolae and caveolin-1 are in the center stage of cholesterol transportation and inflammation in macrophages. Here, we propose that reverse cholesterol transport and inflammation in atherosclerosis can be integrated by caveolae and caveolin-1. |
| Keywords: | caveolae caveolin-1 reverse cholesterol transport inflammation atherosclerosis |