| 滴丸动力黏度的实验研究 |
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| 引用本文： | 王秀宏,方建军.滴丸动力黏度的实验研究[J].北方工业大学学报,2010,22(3):46-50. |
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| 作者姓名： | 王秀宏 方建军 |
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| 作者单位： | 北方工业大学机电工程学院,100144,北京;天津天士力制药股份有限公司,300402,天津;北京联合大学自动化学院,100101,北京 |
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| 摘 要： | 复方丹参滴丸是治疗冠心病等疾病的纯中药固体制剂.在滴丸滴制时,滴丸的动力黏度影响滴丸成品的外观质量,如圆整度、硬度、大小和干裂度等.本文研究复方丹参滴丸制剂的含水率和溶化温度对滴丸动力黏度的影响.通过实验测定和数据分析得出,滴丸制剂的溶化温度在75℃~85℃,滴丸制剂含水率为6%~10%的条件下,滴丸的动力黏度值基本恒定,滴丸的滴制效果最佳.实验结果已经用于制订新的生产工艺,指导实际药品的生产.
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| 关 键 词： | 滴丸 动力黏度 含水量 溶化温度 |
Study on Experiments of Dynamic Viscosity of Chinese Medicine Pills |
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| Wang Xiuhong,Fang Jianjun.Study on Experiments of Dynamic Viscosity of Chinese Medicine Pills[J].Journal of North China University of Technology,2010,22(3):46-50. |
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| Authors: | Wang Xiuhong Fang Jianjun |
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| Affiliation: | Wang Xiuhong1,2) Fang Jianjun3)(1)Col.of Mechanical & Electronical Engineering,North China Univ.of Tech.,100144,Beijing,China,2)Tianjin Tianshili Pharmaceuticals Inc.,300402,Tianjin,3)Col.of Automation,Beijing Union Univ.,100101,China) |
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| Abstract: | The composite Salvia pill is a solid product made from Chinese herbs for curing the coronary heart disease.During the process of production,the dynamic viscosity of the pill(in its liquid form) has an effect on the physical appearance of the product: roundness,hardness,size,crack formation etc.The paper studies the influence of water content and melting temperature of the liquid on the dynamic viscosity of the pill.The study shows that by keeping the melting point and water content within the ranges of 75°C～85°C and 6%～10% respectively,the production will attain its best.The outcome of the research has been formulated into new technology and will serve as a guiding rule in practice. |
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| Keywords: | pills dynamic viscosity water content melting temperature |
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