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Lumbo-sciatica and chemonucleolysis
Authors:F Dubuc  C Rouleau
Abstract:Three patients are described, each having a malignant bone tumor associated with inflammatory episodes in the adjacent joint. Two of these were sarcomas of the lower end of the femur, and one a metastatic carcinoma in the distal end of the radius. Histologically, the synovium exhibited moderate and non-specific signs of inflammation near the malignant tissue. These cases illustrate the possibility of diagnostic error, either clinically or on microscopic examination of small specimens, especially in punch biopsies.
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