| 青冈栎果实抗癌活性的实验研究 |
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| 引用本文： | 甘耀坤,陈旭健,韦敏,叶楚芳,卿莉萍. 青冈栎果实抗癌活性的实验研究[J]. 食品科技, 2010, 0(3) |
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| 作者姓名： | 甘耀坤 陈旭健 韦敏 叶楚芳 卿莉萍 |
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| 作者单位： | 玉林师范学院化学与生物系;玉林市卫生学校; |
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| 基金项目： | 广西科技厅自然基金项目(桂科自0728250); 广西教育厅科研项目(教育厅200709LX140); 广西教育厅科研项目(教育厅200810LX403) |
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| 摘 要： | 目的:研究青冈栎果实提取液的抗癌活性,探讨青冈栎的抗癌机理。方法:在体外培养的胃癌细胞(MGC-803)、子宫颈癌细胞(hela)和肝癌细胞(BEL-7404)中分别采用浓度为0.40、0.81、1.61、3.13、6.25、12.50、25.00mg/mL的青冈栎果实提取液处理,然后利用四甲基偶氮唑蓝法(MTT比色法)定量测定肿瘤细胞的生长抑制情况。结果:青冈栎果实提取液浓度在0.81～25.00mg/mL时对上述3种癌细胞均有抑制效果,其中在25mg/mL浓度下抑制效果最好,对MGC-803、hela和BEL-7404的抑制率分别是72.85%、76.64%、71.81%。结论:青冈栎果实提取液在一定浓度下能抑制体外培养的MGC-803、hela和BEL-7404细胞的生长,显示青冈栎中含有抗癌的有效成分。
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| 关 键 词： | 青冈栎 果实 抗癌活性 |
Experimental study on anti-cancer activity of the fruit Cyclobalanopsis glauca |
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| GAN Yao-kun,CHEN Xu-jian,WEI Min,YE Chu-fang,QING Li-ping. Experimental study on anti-cancer activity of the fruit Cyclobalanopsis glauca[J]. Food Science and Technology, 2010, 0(3) |
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| Authors: | GAN Yao-kun CHEN Xu-jian WEI Min YE Chu-fang QING Li-ping |
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| Affiliation: | GAN Yao-kun1,CHEN Xu-jian1,WEI Min2,YE Chu-fang1,QING Li-ping1 (1.Chemistry , Biology Department of Yulin Normal University,Yulin 537000,2.Health School of Yulin City,Yulin 537000) |
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| Abstract: | Objective:To study Cyclobalanopsis glauca fruit extractive anti-cancer activity,to explore the anticancer mechanism of Cyclobalanopsis glauca.Methods:In vitro cultivation of cells were used in 0.40,0.81,1.61,3.13,6.25,12.50,25 mg/mL density of Cyclobalanopsis glauca fruit extractive and then use MTT method (MTT colorimetric) quantitative measurement of tumor cell growth inhibition of the situation.Results:Cyclobalanopsis glauca fruit extractive in 25 mg/mL concentration of gastric cancer cells show (MGC-803... |
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| Keywords: | Cyclobalanopsis glauca fruit the anti-cancer |
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