| 异核苷杂寡核苷酸的基质辅助激光解吸电离飞行时间质谱测定 |
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| 引用本文： | 张虎翼,杨振军,于宏武,闵吉梅,马灵台,张礼和,彭嘉柔,孙徐林. 异核苷杂寡核苷酸的基质辅助激光解吸电离飞行时间质谱测定[J]. 质谱学报, 1998, 19(4): 8-11 |
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| 作者姓名： | 张虎翼 杨振军 于宏武 闵吉梅 马灵台 张礼和 彭嘉柔 孙徐林 |
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| 基金项目： | 国家自然科学基金!29572037 |
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| 摘 要： | 以芥子酸（sinapinicacid）为基质，对异核苷杂寡核苷酸（3－（R）－IsodT）13·dT和（3－（S）－IsodT）13·dT进行了基质辅助激光解吸电离飞行时间质谱测定，准确地测得分子量，合成的寡核苷酸得以鉴定。
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| 关 键 词： | 飞行时间质谱 质谱 寡核苷酸 异核苷 |
Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry of Oligodeoxynucletides Consisting of Isonucleosides |
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| Zhang Huyi,ang Zhenjun,Yu Hongwu,Min Jimei,Ma Lingtai,Zhang Lihe. Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry of Oligodeoxynucletides Consisting of Isonucleosides[J]. Journal of Chinese Mass Spectrometry Society, 1998, 19(4): 8-11 |
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| Authors: | Zhang Huyi ang Zhenjun Yu Hongwu Min Jimei Ma Lingtai Zhang Lihe |
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| Abstract: | Matrix-assisted laser desorption ionization time-of-flight mass spectrometry of oligodeoxynucleotides consisting of isonucleosides with sinapinic acid as matrix was reported. Modified oligonucleotides were identified by means of their molecular weights obtained. |
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| Keywords: | MALDI-TOFMS oligodeoxynucleotides isonucleosides |
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