| 染料中间体N,N'-1,4-苯基二-(3-氨基-4-甲氧基)苯磺酰胺的合成 |
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| 引用本文： | 李云霞,胡建立,郭芳茹.染料中间体N,N'-1,4-苯基二-(3-氨基-4-甲氧基)苯磺酰胺的合成[J].化学世界,2004,45(10):534-536,525. |
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| 作者姓名： | 李云霞 胡建立 郭芳茹 |
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| 作者单位： | 郑州大学化学系,河南,郑州,450052 |
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| 摘 要： | 以邻氨基苯甲醚、乙酸酐、氯磺酸、对苯二胺为原料,经乙酰化、氯磺化、酰胺化、脱乙酰基等步骤,研究合成了无致癌性染料中间体N,N'-1,4-苯基二-(3-氨基-4-甲氧基)苯磺酰胺。考察了影响酰胺化反应的因素,其优化条件为:反应物用量n(4-甲氧基-3-乙酰氨基-苯磺酰氯)∶n(对苯二胺)为2.2∶1(摩尔比),反应在40°C进行,反应时间为5.0h。产率可达88.46%。产品经红外、核磁、质谱、元素分析等测定确证了结构。
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| 关 键 词： | N N'-1 4-苯基二-(3-氨基-4-甲氧基)苯磺酰胺 染料中间体 邻氨基苯甲醚 对苯二胺 |
| 文章编号： | 0367-6358(2004)10-0534-03 |
Synthesis of a Dye Intermediate:N,N'-1,4-phenylenebis( 3-amino-4-methoxy- benzenesulfonamide ) |
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| LI Yun-xia,HU Jian-li,GUO Fang-ru.Synthesis of a Dye Intermediate:N,N''''-1,4-phenylenebis( 3-amino-4-methoxy- benzenesulfonamide )[J].Chemical World,2004,45(10):534-536,525. |
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| Authors: | LI Yun-xia HU Jian-li GUO Fang-ru |
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| Abstract: | N,N'-1,4-phenylenebis3-amino-4-methoxyx-benzenesulfonamide] was synthesized from o-aminoanisole and p-phenylene, diamine and the product was characterized by IR, ~1H NMR and MS. The factors affecting the yield were investigated. The results showed that the optimum conditions are as follows: 4-methoxy-3-acetylamino-benzenesulfonylchloride:p-phenylene diamine, 2.2∶1(mol); reaction temperature,40°C; reaction time, 5.0 h. The yield is above 88.64% under optimum conditions. |
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| Keywords: | N N'-1 4-phenylene bis[3-amino-4-methoxy-benzenesulfonamide] dye intermediate o-aminoanisole p-phenylene diamine |
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