Abstract: | Over the past decade, the subject of “greener chemistry" and chemical processes has been emphasized. The “greener chemistry” improves environmental efficiency in reducing the consumption of resources and energy and achieving a stable economic development of the environment. Nanotechnology is investigating nanoscale materials that have applications in the area of biotechnology and nanomedicine alongside several other significant applications such as cosmetics, drug delivery, and biosensors. The different shapes and sizes of nanoparticles can be synthesized with physical, chemical, or biological methods. The tendency to produce nanomaterials, especially metal oxides, and use them, is increasing because of their exciting properties in the nanoscale. However, metal oxide nanoparticles produced by chemical methods have significant concerns due to hazardous and toxic chemicals and their environmental damage. The production of metal oxide nanoparticles using the principles of greener chemistry has found a special place in research. Increased awareness of greener chemistry and biological processes has necessitated using environmentally friendly methods for the production of non-toxic nanomaterials. Plants and polymeric materials as renewable and inexpensive sources have received particular attention to prepare nano biomaterials. The use of plants to synthesize metal oxide nanoparticles because of the non-use toxic pollutants is one of the environmentally friendly methods, and that's why this type of synthesis is called greener synthesis. In this review, we exhibit a total sight of greener synthesis methods for producing metal oxide nanoparticles and their medical applications. |