Polyacrylamide-gelatin polymeric networks: effect of pH and gelatin concentration on the swelling kinetics and mechanical properties

This work presents the synthesis of polyacrylamide-gelatin (PAM-G) semi-interpenetrating hydrogels, as well as the study of the swelling capacity of this material at different pH’s, and we report its Young modulus. The hydrogels were crosslinked with N,N′-methylenebisacrylamide and synthesized at different acrylamide/gelatin weight relationship. It was observed that the swelling capacity of the hydrogels increases when the gelatin concentration is increased; while the Young modulus (at the swelling equilibrium) decreases lightly. Therefore, the gelatin has a small effect in the Young modulus, unlike its influence in the swelling ability. The swelling experiments reveal that the PAM-G hydrogels increase its swelling capacity in alkaline mediums because the presence of the hydrophobic functional groups (mainly COO⁻) in the gelatin structure.