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Synthesis of a Potential Tumor Imaging Agent by Oxidative Radioiodination of Aspirin and Its Preclinical Study |
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| Authors: | Ibrahim I T Attallah K H Elsaid M Fahmy M H Abo Zaid L A |
| Affiliation: | 1.Hot Laboratories Centre, Atomic Energy Authority, P.O. Box 13759, Cairo, Egypt ;2.Pharmaceutics Department, Faculty of Pharmacy, Umm Al-Qura University, Mecca, Saudi Arabia ;3.Biochemistry Department, Faculty of Pharmacy, Qassim University, Buraydah, Saudi Arabia ;4.Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt ;5.Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Delta University, Gumassa, Egypt ; |
| Abstract: | Radiochemistry - Aspirin, one of nonsteroidal anti-inflammatory analgesic drugs, was labeled with 125I with a labeling yield of 85.5% under the following conditions: pH 9, 100 mg of the substrate,... |
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