Diffusion–Drift Modeling of a Growing Breast Cancerous Cell |
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Authors: | Hassan AM El-Shenawee M |
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Affiliation: | Dept. of Electr. Eng., Univ. of Arkansas, Fayetteville, AR, USA; |
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Abstract: | This paper presents a 2-D model to calculate the electric current densities and the biopotential differences generated due to a breast cancerous cell during the hyperpolarization of the G1/synthesis (G1/S) transition. The proposed model is based on semiconductor diffusion-drift analysis, and aims to understand the biophysics associated with growing breast cancerous cells. The effect of the duration of the G1/S transition, and the diffusivity and the mobility of the cancerous cell boundary is investigated. The results show that shorter G1/S transition durations, and higher diffusivity and mobility at the cell boundary provide higher magnitude of the electric signals. |
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