| 竹红菌素光动力疗法抗肿瘤的生物学机制 |
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| 引用本文： | 夏新蜀,白定群,余和平,李小宏,许川山.竹红菌素光动力疗法抗肿瘤的生物学机制[J].四川激光,2011(6):52-54. |
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| 作者姓名： | 夏新蜀 白定群 余和平 李小宏 许川山 |
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| 作者单位： | [1]重庆医科大学附属第一医院康复医学科,重庆400016 [2]香港中文大学中医药学院,香港 |
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| 基金项目： | 国家自然科学基金资助项目（81071824） |
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| 摘 要： | 竹红菌素（hypocrellins）是我国首先研究的一类天然光敏剂,具有结构明确、光敏化活性高、暗毒性低、体内代谢快等特性,在临床光动力治疗实践中具有良好的应用前景。本文仅就竹红菌素光动力疗法抗肿瘤的生物学机制进行综述与探讨。
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| 关 键 词： | 竹红菌素 光动力学疗法 抗肿瘤 生物学机制 |
Biological mechanism of photodynamic therapy with hypocrellin on tumor |
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| XIA Xin-shu,BAI Ding-qun,YU He-ping,LI Xiao-hong,XU Chuan-shan.Biological mechanism of photodynamic therapy with hypocrellin on tumor[J].Laser Journal,2011(6):52-54. |
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| Authors: | XIA Xin-shu BAI Ding-qun YU He-ping LI Xiao-hong XU Chuan-shan |
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| Affiliation: | 1.Department of Rehabilitation Medicine,First Affiliated Hospital,Chongqing Medical University,Chongqing 400016,China;2.School of Chinese Medicine,The Chinese University of Hong Kong,Shatin,Hong Kong,China) |
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| Abstract: | Hypocrellin is a naturally occurred photosensitizer,isolating from traditional China medicine.It has many great characteristics of ideal photosenisitizer,for example,definited structure,high photosensitive activity,low dark toxicity and fast metabolism.Therefore,hypocrellin as a new sensitizer play an important role in PDT area.The present paper reviewed the biological mechanism of hypocrellin-based PDT on tumor. |
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| Keywords: | hypocrellin photodynamic therapy tumor biological mechanism |
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