| 铅暴露对发育期大鼠肾脏超微结构影响 |
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| 引用本文： | 刘文波,刘同慎,杨成,张瑾锦. 铅暴露对发育期大鼠肾脏超微结构影响[J]. 电子显微学报, 2011, 30(3): 232-238 |
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| 作者姓名： | 刘文波 刘同慎 杨成 张瑾锦 |
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| 作者单位： | 1. 滨州医学院 医学研究中心
2. 滨州医学院 组织胚胎学教研室,山东烟台,264003 |
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| 摘 要： | 目的:从光镜和电镜水平观察铅暴露对发育期雄性大鼠肾组织的形态学影响.方法:3周龄SD雄性大鼠,随机分为对照组和染铅组.染铅组腹腔注射0.2%乙酸铅溶液(0.2 mL/100 g体质量),隔日1次,共20次,对照组同时注射生理盐水.实验结束后,测量各组动物血铅和血中游离原卟啉,取肾组织作光镜和透射电镜观察.结果:与对照组...
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| 关 键 词： | 铅暴露 肾脏 超微结构 核内铅包涵体 |
Affects on ultrastucture of kidney in developmental lead exposed rats |
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| LIU Wen-bo,LIU Tong-shen,YANG Cheng,ZHANG Jin-jin. Affects on ultrastucture of kidney in developmental lead exposed rats[J]. Journal of Chinese Electron Microscopy Society, 2011, 30(3): 232-238 |
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| Authors: | LIU Wen-bo LIU Tong-shen YANG Cheng ZHANG Jin-jin |
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| Affiliation: | LIU Wen-bo1,LIU Tong-shen2,YANG Cheng1,ZHANG Jin-jin1(1.Medicine Research Center,2.Department of histology and embryology,Binzhou Medical College,Yantai Shandong 264003,China) |
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| Abstract: | Objective: To investigate the morphological changes in kidney of developmental male rats caused by lead exposure from the level of light and electron microscopy.Method: 3-week-old male SD rats were randomly divided into control group and lead group.Rats in lead group were given 0.2% lead acetate solution by intraperitoneal injection(0.2 ml/100g body mass) once every other day,a total of 20,while rats in control group were given normal saline instead.The contents of blood lead and free protoporphyrin of rats... |
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| Keywords: | lead exposure kidney ultrastructure intranuclear lead inclusion body |
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