| 金盏银盘提取物对α-葡萄糖苷酶的抑制作用研究 |
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| 引用本文： | 韦国兵,熊巍.金盏银盘提取物对α-葡萄糖苷酶的抑制作用研究[J].山东化工,2012,41(9):1-3. |
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| 作者姓名： | 韦国兵 熊巍 |
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| 作者单位： | 江西中医学院药学院,江西南昌,330006 |
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| 基金项目： | 江西省教育厅课题（GJJ10213）;江西省卫生厅课题（20088003） |
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| 摘 要： | 对金盏银盘醇提取物用石油醚、乙酸乙酯和正丁醇进行萃取,测定各部分的酶抑制活性,并初步对金盏银盘酶抑制的动力学进行研究。结果表明:乙酸乙酯部位具有较高的α-葡萄糖苷酶抑制活性,其抑制成分在35～55℃具有较高的稳定性,最佳作用浓度为45μg/mL,且抑制作用迅速。
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| 关 键 词： | 金盏银盘 α-葡萄糖苷酶抑制 提取物 |
Preliminary Study on the α-Glucsidase Inhibitor from Bidens Biternata |
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| WEI Guo - bing,XIONG Wei.Preliminary Study on the α-Glucsidase Inhibitor from Bidens Biternata[J].Shandong Chemical Industry,2012,41(9):1-3. |
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| Authors: | WEI Guo - bing XIONG Wei |
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| Affiliation: | ( College of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China) |
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| Abstract: | The extract of Bidens biternata was extracted by petroleum, ethyl acetate and n - butanol. The inhibitiory activity against α-glucsidase of every extracted fraction was detemined and the inhibitory kinetics was studied. The results showed that the inhibitiory activity of ethyl acetate was higher than others. Betwen 35 - 55℃ the ethyl acetate extract showed high thermal stability, and the optimum concentration was 45 μg/mL. |
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| Keywords: | Bidens biternata α-glucsidase inhibitor extract |
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