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| 地奥司明片制备工艺的研究 | |
| 引用本文： | 朱忠华,朱世龙,朱世仁,马艳.地奥司明片制备工艺的研究[J].广东化工,2010,37(3):98-100. |
| 作者姓名： | 朱忠华 朱世龙 朱世仁 马艳 |
| 作者单位： | 1. 湖北省医药学校,湖北,武汉,430064 2. 浙江杭州杭化播磨造纸化学品有限公司,浙江,杭州,311231 3. 江西师范大学,数学系,江西,南昌,330022 |
| 摘 要： | 以脆碎度、崩解时间及溶出度为考察指标,对地奥司明片处方及工艺进行研究,按选定处方及工艺制备出的样品与进口地奥司明片进行溶出度的对比试验,结果表明,自制地奥司明片溶出情况与进口片基本一致。 |
| 关 键 词： | 地奥司明 爱脉朗 正交试验 脆碎度 溶出度 |
Study on the Formulation and Preparation of Diosmin Tablets |
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| Zhu Zhonghua,Zhu Shilong,Zhu Shiren,Ma Yan.Study on the Formulation and Preparation of Diosmin Tablets[J].Guangdong Chemical Industry,2010,37(3):98-100. | |
| Authors: | Zhu Zhonghua Zhu Shilong Zhu Shiren Ma Yan |
| Affiliation: | 1. Hubei Pharmaceutical School, Wuhan 430064; 2. Hangzhou Hanghua Harima Paper Chemicals Co., Ltd., Hangzhou 311231 ; 3. Department of Mathematics, Jiangxi Normal University, Nanchang 330022, China) |
| Abstract: | The formulation and technology of diosmin tablets were optimized using the diameter of diosmin, disintegration time and fragility as indexes. The diosmin tablets that were made by the optimized formulation and technology were compared with the Alvenor by dissolution. The results indicated that the dissolve curve of the self-made tablets was similar to the curve of Alvenor. The results showed that the selected formulation and technology was corrected. |
| Keywords: | diosmin Alvenor orthogonal experiment design fragility dissolution |
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