Liquid chromatographic separation of xylene isomers on α-cyclodextrin bonded phases |
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Authors: | Manhoe Kim J Douglas Way Robert M Baldwin |
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Affiliation: | (1) Department of Chemistry, Air Force Academy (R.O.K.), Cheong-ju, 363-849 Chungbuk, Korea;(2) Chemical Engineering Department, Colorado School of Mines, CO 80401 Golden, USA |
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Abstract: | Mesoporous glass beads and silica were modified with α-cyclodextrin (CD) for the separation of xylene isomers by means of
direct bonding, linking spacer group, and cross-linking agent. The separation efficiency of the (α-CD modified silica particles
was tested by using simple column chromatography. A strong inclusion complex formation of p-xylene was observed from the column
packed with α-CD bonded phases. Spacer group and crosslinking agent decreased the formation of the inclusion complex of p-xylene
and increased selectivity between m-xylene and o-xylene. The inclusion complex formation of p-xylene was strongly diminished
when the mobile phase was switched from methyl alcohol to toluene. The column packed with the cross-linked a-CD bonded silica
showed the best performance in the separation of xylene isomers. |
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Keywords: | Mesoporous Glass Beads Silica α -Cyclodextrin Xylene Separation Chromatography Inclusion Complex |
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