Current developments in chemistry,coordination, structure and biological aspects of 1-(acyl/aroyl)-3- (substituted)thioureas: advances Continue?… |
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| Authors: | Aamer Saeed Muhammad Naeem Mustafa Muhammad Zain-ul-Abideen Ghulam Shabir Mauricio F Erben Ulrich Flörke |
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| Affiliation: | 1. Department of Chemistry, Quaid-i-Azam University-45320, Islamabad, Pakistanaamersaeed@yahoo.com;3. Department of Chemistry, Quaid-i-Azam University-45320, Islamabad, Pakistan;4. CEQUINOR (UNLP, CONICET-CCT La Plata), Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata La Plata, República Argentina;5. Department Chemie, Fakult?t für Naturwissenschaften, Universit?t Paderborn Paderborn, Germany |
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| Abstract: | 1-(acyl/aroyl)-3-(substituted)thioureas are exciting structures in the fields of organic synthesis, material sciences, and biomedical research. Of particular significance is the fact that acyl thiourea derivatives have been demonstrated to be highly exceptional ligands and their coordination compounds have extensively been investigated in the synthesis of pharmaceuticals and agrochemical ingredients. Moreover, these structural motifs are enjoying the prestigious status as versatile synthons in heterocyclic syntheses. Therefore, the progress to introduce functionalization on the backbone of 1-(acyl/aroyl)-3-(substituted)thioureas is highly desirable. This account summarizes our efforts to capture recent documented achievements by various research groups. |
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| Keywords: | Acyl thiourea molecular structure liquid crystals chemosensors catalyst medicinal bioactive |
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