| 铜和硫酸铜选择性催化合成单取代苯基哌嗪的新方法 |
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| 引用本文： | 童荣标,郭灿城.铜和硫酸铜选择性催化合成单取代苯基哌嗪的新方法[J].化学试剂,2003,25(4):239-240. |
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| 作者姓名： | 童荣标 郭灿城 |
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| 作者单位： | 湖南大学化学化工学院,湖南,长沙,410082 |
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| 摘 要： | 报道了无溶剂条件下用铜和硫酸铜作催化剂由溴苯与哌嗪选择性合成单取代苯基哌嗪的新方法，并初步研究了溶剂、反应时间、反应温度对反应产率的影响。
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| 关 键 词： | 铜 硫酸铜 选择性催化合成 单取代苯基哌嗪 药物化学 催化剂 |
| 文章编号： | 0258-3283(2003)04-0239-02 |
| 修稿时间： | 2002年7月25日 |
A novel synthetic method for mono substituted phenylpiperazine selectively catalyzed by copper and copper sulfate |
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| TONG Rong-biao,GUO Can-cheng.A novel synthetic method for mono substituted phenylpiperazine selectively catalyzed by copper and copper sulfate[J].Chemical Reagents,2003,25(4):239-240. |
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| Authors: | TONG Rong-biao GUO Can-cheng |
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| Abstract: | A novel synthetic method for mono substituted phenylpiperazine from the reaction of phenylbromide with piperazine selectively catalyzed by copper and copper sul-fate without any solvent was developed. The effects of reaction temperature, time and solvent on the yields were discussed. |
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| Keywords: | catalytic synthesis copper and copper sulfate phenylpiperazine |
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