| 去甲斑蝥素硫脲类衍生物的设计及合成 |
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| 引用本文： | 魏初铨,孙晓飞,李泳秀.去甲斑蝥素硫脲类衍生物的设计及合成[J].化学试剂,2010,32(2). |
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| 作者姓名： | 魏初铨 孙晓飞 李泳秀 |
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| 作者单位： | 苏州大学,医学部,药学院,江苏,苏州,215123 |
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| 摘 要： | 寻找新型抗惊厥化合物,设计合成了标题化合物。6个目标化合物的结构经IR、1HNMR和HR-MS进行了确证,并优化了合成反应的条件。
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| 关 键 词： | 抗惊厥 去甲斑蝥素 硫脲 γ-氨基丁酸 γ-aminobutyric acid |
Design and synthesis of the thiourea derivatives of norcantharidin |
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| WEI Chu-quan,SUN Xiao-fei,LI Yong-xiu.Design and synthesis of the thiourea derivatives of norcantharidin[J].Chemical Reagents,2010,32(2). |
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| Authors: | WEI Chu-quan SUN Xiao-fei LI Yong-xiu |
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| Abstract: | In order to find new anticonvulsant compounds,the authors had designed and synthesize the thiourea derivatives of norcantharidin.The structures of the six target compounds were identified by IR,~1HNMR and HR-MS,and the reaction conditions were optimized. |
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| Keywords: | anticonvulsant norcantharidin thiourea |
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