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| 那他霉素微胶囊的制备及性能测试 | |
| 引用本文： | 郑雅婧,卢向阳,巨修练,卢彩鸽,刘伟成,高攀.那他霉素微胶囊的制备及性能测试[J].农药,2012,51(4):267-269. |
| 作者姓名： | 郑雅婧 卢向阳 巨修练 卢彩鸽 刘伟成 高攀 |
| 作者单位： | 1. 武汉工程大学化工与制药学院,武汉,430074 2. 北京市农林科学院植物保护环境保护研究所,北京,100097 3. 长江大学农学院,湖北荆州,434023 |
| 基金项目： | 北京市科技计划，北京市农林科学院项目，北京市农林科学院植环所创新基金项目 |
| 摘 要： | 目的]利用微胶囊技术提高那他霉素(NA)的抗光解性能.方法]复凝聚法,以明胶和阿拉伯胶作壁材,以正交试验优化工艺,测试微胶囊释放和抗光解.结果]优化工艺为壁材质量浓度20 g/L、芯壁比1.5∶1、反应pH值4.5、反应时间90 min；以水和30％甲醇溶液为释放介质,微胶囊具良好的通透性和缓释性；在紫外光下,NA微胶囊相对活性下降50％的时间为79 min,较NA浓缩液和NA悬乳剂(含UV-531)分别提高3.0倍和1.1倍.结论]NA微胶囊可显著提高NA的抗光解性能,作为农用杀菌剂具较大潜力. |
| 关 键 词： | 那他霉素 微胶囊 复凝聚法 抗光解 |
Preparation of Natamycin Microcapsule and Its Properties |
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| ZHENG Ya-jing , LU Xiang-yang , JU Xiu-lian , LU Cai-ge , LIU Wei-cheng , GAO Pan.Preparation of Natamycin Microcapsule and Its Properties[J].Pesticides,2012,51(4):267-269. | |
| Authors: | ZHENG Ya-jing LU Xiang-yang JU Xiu-lian LU Cai-ge LIU Wei-cheng GAO Pan |
| Affiliation: | 1.School of Chemical Engineering & Pharmacy,Wuhan Institute of Technology,Wuhan 430074,China; 2.Institute of Plant & Enviromental Protection,Beijing Academy of Agricultural and Forestry Science,Beijing 100097,China;3.Agriculture College,Yangtze University,Jingzhou 434023,Hubei,China) |
| Abstract: | Aims] Microcapsulation was utilized to increase natamycin(NA) photostability.Methods] With gelatin and gum arabic as wall materials,NA microcapsule was prepared by complex coacervation and the process was optimized with orthogonal test.And also its release and anti-photolysis were determined.Results] Optimal process was as follows: 20 g/L concentration of wall material,core/wall 1.5∶1(w/w),reaction pH 4.5 and reaction time 90 min.Good permeability and control release of the microcapsule were got in water and 30% methanol solution.It took 79 min for the relative activity of the microcapsule to decrease by 50% under UV,which increased by 3.0 and 1.1 times compared with NA concentrate and susupended emulsion with UV-531,respectively.Conclusions] The microcapsule could significantly improve NA photostability and showed a good prospect as agricultural fungicide. |
| Keywords: | natamycin microcapsule complex coacervation anti-photolysis |
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