亚胺唑在梨上的残留行为及膳食风险评估

[目的]研究亚胺唑在梨上的残留行为,并进行膳食风险评估,建立了梨中亚胺唑的残留检测方法.[方法]样品经乙腈提取,C18净化,利用超高效液相色谱-串联三重四级杆质谱仪(UPLC-MS/MS)检测.[结果]在0.001 ～1.0 mg/L范围内,亚胺唑的线性关系良好,R2为0.9981(R2＞0.99);在0.005、0....

Residual Behavior and Dietary Risk Assessment of Imibenconazole in Pears

[Aims] This paper aims to study the residue behavior of imibenconazole on pear and evaluate the dietary risk, a method for residues analysis of imibenconazole in pears was established. [Methods] The samples were extracted with acetonitrile, purified with C18, and detected by ultra performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS). [Results] The result showed all the correlation coefficient of calibration curves were over 0.99 ranging from 0.001 to 1.0 mg/L. At the level of 0.005, 0.01, 0.05 and 0.5 mg/kg, the recovery of imibenconazole in pears was 82 to 98%, RSD was 4 to 14%, and the limit of quantification was 0.005 mg/kg. The half-life of imibenconazole was 16.5 to 16.9 days;the average residue of imibenconazole in pears was 0.16 to 2.7, 0.033 to 0.78,0.042 to 0.69, 0.012 to 0.54 mg/kg of 0, 14, 21, 28 days after the last application. Given that the national estimated daily intake(NEDI) of chlorothalonil was 0.0055 mg, its risk quotient(RQ) was 0.9%. [Conclusions] The residual amount of imazole in pears gradually decreased with the extension of harvest interval, and there was no unacceptable risk to the health of the general population. Therefore, it is suggested that when 15% imidazole wettable powder is used on pears,the maximum dosage is 50 mg/L of liquid, the maximum dosage is 3 times, the interval of application is 7 days, and the safe interval is 28 days.