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Chondroitin sulfate: extraction,purification, microbial and chemical synthesis
Authors:Yu‐gang Shi  Yue‐cheng Meng  Jian‐rong Li  Jie Chen  Yu‐hua Liu  Xue Bai
Affiliation:1. School of Food Science and Biotechnology Engineering, Zhejiang Gongshang University, Food Safety Key Lab of Zhejiang Province, , HangZhou, 310035 China;2. Department of Chemistry, University of Toronto, , Toronto, M5S 3H6 Canada;3. College of Chemistry, Chemical Engineering and Food Safety, Bohai University, , Jinzhou, 121013 China
Abstract:Chondroitin sulfate, a type of acid mucopolysaccharide possessing a variety of bioactivities, has attracted tremendous interest due to its use in the relief of joint diseases. It has been widely applied in different fields, such as medicine, biotechnology, pharmacy, textiles, food and cosmetics. This mini‐review focuses on the main methods of its extraction and purification, and recent advances in bio‐syntheses and chemical synthesis of such molecules. In addition, further studies in these aspects are proposed based on current research. © 2014 Society of Chemical Industry
Keywords:chondroitin sulfate  extraction  purification  bio‐synthesis  chemical synthesis
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