| 5-乙酰乙酰氨基苯并咪唑酮合成工艺研究 |
| |
| 引用本文： | 章振宇,张 静,申海蛟,马建宇,周立山,曲红梅.5-乙酰乙酰氨基苯并咪唑酮合成工艺研究[J].化学工业与工程,2014(1):24-27. |
| |
| 作者姓名： | 章振宇 张 静 申海蛟 马建宇 周立山 曲红梅 |
| |
| 作者单位： | 天津大学化工学院,天津300072 |
| |
| 基金项目： | 天津大学2012年大学生创新训练计划项目资助（201210056304）. |
| |
| 摘 要： | 以5-硝基苯并咪唑酮为原料,采用水合肼还原制备5-氨基苯并咪唑酮(BI),反应条件温和,安全,环境友好。研究了溶剂对BI合成5-乙酰乙酰氨基苯并咪唑酮(AABI)的影响:在乙酸乙酯中,BI与双乙烯酮反应合成AABI,收率可达89.3%。
|
| 关 键 词： | 水合肼 还原 -氨基苯并咪唑酮 -乙酰乙酰氨基苯并咪唑酮 |
Synthesis of 5-Acetylacetamidobenzimidazolone |
| |
| Zhang Zhenyu,Zhang Jing,Shen Haijiao,Ma Jianyu,Qu Hongmei.Synthesis of 5-Acetylacetamidobenzimidazolone[J].Chemical Industry and Engineering,2014(1):24-27. |
| |
| Authors: | Zhang Zhenyu Zhang Jing Shen Haijiao Ma Jianyu Qu Hongmei |
| |
| Affiliation: | (School of Chemical Engineering and Technology, Tianjin University,Tianjin 300072, China) |
| |
| Abstract: | 5-aminobenzimidazolone was prepared from 5-nitrobenzimidazolone by hydrazine hydrate reduction. This method is mild, safe and environmentally friendly. The effect of solvents on the preparation of 5-acetylacetamidobenzimidazolone was studied. When ethyl acetate was used as solvent in this reaction, 5-acetylaeetamidobenzimidazolone was synthesized by the reaction of 5-amino benzimidazolone with diketene, the yield was 89.3%. |
| |
| Keywords: | hydrazine hydrate reduction 5-aminobenzimidazolone 5-acetylacetamidobenzimidazolne |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
