| α型基因工程干扰素栓剂治疗宫颈糜烂的临床研究 |
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| 引用本文： | 马晓艳,王占东,安启哲,陈维佳,郭德本,李财.α型基因工程干扰素栓剂治疗宫颈糜烂的临床研究[J].粉末涂料与涂装,1995(3). |
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| 作者姓名： | 马晓艳 王占东 安启哲 陈维佳 郭德本 李财 |
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| 作者单位： | 白求恩医科大学第二临床学院!长春，130041，白求恩医科大学第二临床学院!长春，130041，白求恩医科大学第二临床学院!长春，130041，卫生部长春生物制品研究所，卫生部长春生物制品研究所，卫生部长春生物制品研究所 |
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| 摘 要： | 采用α型基因工程干扰素（rIFN－α）栓剂宫颈局部连续用药，治疗中重度宫颈糜烂120例，并以洗必泰栓及CO2激光治疗作为对照。结果表明，治疗组痊愈率、显效率及有效率均明显高于对照组（P＜0．01）。在治疗组中，使用5×105IUrIFN－α栓剂者的上述指标明显高于使用1×105IU栓剂者（p＜0．005）。采用5×105IUrIFN－α治疗后，人巨细胞病毒（HCMV）阴转率与疗效呈正相关。
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| 关 键 词： | 基因工程干扰素 宫颈糜烂 巨细胞病毒 鳞状上皮化 |
Clinical Study on Treatment of Cervical Erosion with IFN-α Suppository |
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| Ma Xiaoyan et al.Clinical Study on Treatment of Cervical Erosion with IFN-α Suppository[J].Chinese Journal of Biologicals,1995(3). |
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| Authors: | Ma Xiaoyan |
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| Abstract: | 120 cases of Ⅱ～Ⅲ°cervical erosion were treated by continuous local adminis-tration of TFN - α suppository,using Hibitane suppository of CO2 laser as control. The resultshowed that the cure,cexellent effective and effective rates of the treated group were signifi-cantly higher than those of control. In the treated group,however,the above mentioned cura-tive indexes of the cases received 5×105 IUrFN -α were significantly higher than those re-ceived 1 ×105 IU, In addition, the human cytomegalovirus (HCMV)conversion rate of themshowed a paraller relationship with curative effects. |
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| Keywords: | rIFN-α Cervical Erosion HCMV |
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