| 溶剂法合成2-羟基-1-萘甲酸的工艺研究 |
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| 引用本文： | 沈玉堂,漆琳,殷恒波,刘于民,姜廷顺.溶剂法合成2-羟基-1-萘甲酸的工艺研究[J].精细化工中间体,2008,38(5). |
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| 作者姓名： | 沈玉堂 漆琳 殷恒波 刘于民 姜廷顺 |
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| 作者单位： | 江苏大学,化学化工学院,江苏,镇江,212013 |
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| 基金项目： | 江苏大学校科研和教改项目 |
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| 摘 要： | 以β-萘酚和氢氧化钠为原料,正辛烷为溶剂,合成了2-羟基-1-萘甲酸,纯度达98%以上。通过正交实验研究了反应压力、反应温度和反应时间对收率的影响,确定了优化的工艺条件:反应压力0.8 MPa,反应温度90℃,反应时间8 h,该条件下收率达82.83%。
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| 关 键 词： | 2-羟基-1-萘甲酸 Kolbe-Schmitt反应 溶剂法 正交实验 正辛烷 |
Study on Synthesis Process of 2-Hydroxy-1-naphthoic Acid by Solvent |
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| SHEN Yu-tang,QI Lin,YIN Heng-bo,LIU Yu-min,JIANG Ting-shun.Study on Synthesis Process of 2-Hydroxy-1-naphthoic Acid by Solvent[J].Fine Chemical Intermediates,2008,38(5). |
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| Authors: | SHEN Yu-tang QI Lin YIN Heng-bo LIU Yu-min JIANG Ting-shun |
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| Affiliation: | SHEN Yu-tang,QI Lin,YIN Heng-bo,LIU Yu-min,JIANG Ting-shun(Faculty of Chemistry , Chemical Engineering,Jiangsu University,Zhenjiang 212013,China) |
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| Abstract: | 2-Hydroxy-1-naphthoic acid was prepared from β-naphthol and sodium hydroxide in n-octane,and its purity was up to 98%.The effects of the reaction pressure,temperature and time on the yield of the product were investigated by orthogonal test,and the optimal conditions were obtained.Under the optimum conditions such as: reaction pressure 0.8 MPa,reaction temperature 90℃ and reaction time 8 h,the yield of the product was 82.83%. |
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| Keywords: | 2-hydroxy-1-naphthoic acid Kolbe-Schmitt reaction solvent method orthogonal test n-octane |
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