Lipid analog with 2-nitrophenol trigger designed for liposome fusion at physiological pH |
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| Authors: | S N Shah Takenori Tomohiro Yoshikatsu Ogawa Masato Kodaka Hiroaki Okuno |
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| Affiliation: | (1) Present address: Polymer Science Research Center, The University of Southern Mississippi, P.O. Box 10076, 39406 Hattiesburg, MS;(2) Biomolecules Department, National Institute of Bioscience and Human-Technology, 1-1 Higashi, 305-8566 Tsukuba, Ibaraki, Japan |
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| Abstract: | A novel lipid analog with two long alkyl (C16) chains, an aspartate skeleton, a connecting alkyl (C8) chain, and 2-nitrophenol trigger group is synthesized by an efficient synthetic route, which can induce liposome fusion
at physiological pH. |
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