对甲苯磺酸铜催化合成对羟基苯甲酸乙酯的研究

研究了以对羟基苯甲酸、乙醇为原料、对甲苯磺酸铜为催化剂、合成对羟基苯甲酸乙酯，并讨论了催化酯化的影响因素。实验结果表明，对甲苯磺酸铜是合成对羟基苯甲酸乙酯的良好催化剂，优化的反应条件为：对羟基苯甲酸用量为0．10mol，醇酸摩尔比为4：1，甲苯磺酸铜用量为2．2g，回流温度下反应4．0h，在此实验下酯化率可达94．3％。产品经傅立叶红外光谱仪及熔点仪表征，证实与目标产物完全一致。

Study on the Catalytic Synthesis of Ethyl p -Hydroxybenzoate by Copper p -Toluene Sulfonate

The preparation of ethyl p-hydroxybenzoate by the catalytic reaction of p-hydroxybenzoic acid with ethanol with copper p-toluene sulfonate as catalyst had been studied.The effect of different factors such as the mole ratio of alcohol to acid,the dosage of catalyst,reaction time on the yield of ethyl p-hydroxybenzoate were investigated.The results showed that the optimized reaction conditions were as follows: when the amount of p-hydroxybenzoic acid was 0.10mol,the molar ratio of ethanol to the acid was 4:1,the amount of catalyst was 2.2g, and reaction time was 4.0h at reflux temperature,the esterification yield reached to 94.3%.The product was characterized by FT-IR spectrum and melting point determination. Product was consistent with the target product.