| 5-硝基水杨醛的合成研究 |
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| 引用本文： | 曹志武,刘俊峰,姜鹏,冯桂英.5-硝基水杨醛的合成研究[J].广州化工,2011(24):47-48,63. |
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| 作者姓名： | 曹志武 刘俊峰 姜鹏 冯桂英 |
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| 作者单位： | 湖南科技大学化学化工学院 |
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| 基金项目： | 湖南科技大学研究生创新基金资助(S100122) |
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| 摘 要： | 以对硝基苯酚、乌洛托品、多聚甲醛等为原料合成5-硝基水杨醛,主要探讨了反应温度、时间、反应物用量及酸等因素对合成产率的影响。较优反应条件为：在对硝基苯酚为0.02 mol（2.78 g）的情况下,多聚甲醛用量为0.4 g,冰醋酸和乙酸酐分别为15 mL和8 mLn,（六亚甲基四胺）：n（对硝基苯酚）=2∶1,反应时间为4.0 h,反应温度为90℃,此时反应产率可达78.9%。产品经IR表征。
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| 关 键 词： | 对羟基苯甲酸 乌洛托品 5-硝基水杨醛 |
Synthesis of 5-nitrosaicyl Aldehyde |
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| CAO Zhi-wu,LIU Jun-feng,JIANG Peng,FENG Gui-ying.Synthesis of 5-nitrosaicyl Aldehyde[J].GuangZhou Chemical Industry and Technology,2011(24):47-48,63. |
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| Authors: | CAO Zhi-wu LIU Jun-feng JIANG Peng FENG Gui-ying |
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| Affiliation: | (Academy of Chemistry and Chemical Engineering,Hunan University of Science and Technology, Hunan Xiangtan 411201,China) |
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| Abstract: | 5-nitrosaicyl aldehyde was synthesized by reaction of p-nitrophenol,hexamethylenetetramine and paraformalclehyde.The optimum conditions were as follows: n(urotropine)/n(5-nitrosaicyl aldehyde)=2:1,the reaction time about 4.0 h,temperature about 90 ℃,the amount of the paraformalclehyde 0.4 g,glacial acetic acid 15 mL,and acetic anhydride 8 mL.The yield can reach 69.5%.The product was characterized by IR. |
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| Keywords: | 4-hydroxbenzoic acid hexamethylenetetramine 5-nitrosaicyl aldehyde |
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