| 高效液相色谱法同时测定化妆品中的4种禁用着色剂 |
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| 引用本文： | 郭桂媛,林维宣,金红利,于一茫,侯红漫.高效液相色谱法同时测定化妆品中的4种禁用着色剂[J].日用化学工业,2011,41(3):229-231. |
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| 作者姓名： | 郭桂媛 林维宣 金红利 于一茫 侯红漫 |
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| 作者单位： | 1. 大连工业大学,辽宁大连,116034
2. 辽宁省出入境检验检疫局,辽宁大连,116001 |
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| 摘 要： | 建立了高效液相色谱-紫外-可见光检测器(HPLC/UV-Vis)同时测定化妆品中4种禁用着色剂的检测方法。化妆品样品以乙醇为溶剂进行萃取,然后以萃取液作为检测对象,采用C18反相色谱柱,以乙腈-0.5% H3PO4溶液为流动相进行梯度洗脱,用紫外-可见光检测器检测,定量检测波长530 nm。方法的平均回收率(n=8)为86%～100%,相对标准偏差(RSD)为3.68%～8.02%;碱性紫1、颜料橙5、苏丹蓝2、苏丹红IV的检出限分别为0.05,0.5,0.5,0.2μg/mL。
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| 关 键 词： | 化妆品添加剂 高效液相色谱法 着色剂 |
Simultaneous determination of four forbidden colorants in cosmetics by HPLC |
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| GUO Gui-yuan,LIN Wei-xuan,JIN Hong-li,YU Yi-mang,HOU Hong-man.Simultaneous determination of four forbidden colorants in cosmetics by HPLC[J].China Surfactant Detergent & Cosmetics,2011,41(3):229-231. |
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| Authors: | GUO Gui-yuan LIN Wei-xuan JIN Hong-li YU Yi-mang HOU Hong-man |
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| Affiliation: | GUO Gui-yuan1,LIN Wei-xuan2,JIN Hong-li1,YU Yi-mang2,HOU Hong-man1(1.Dalian Polytechnic University,Dalian,Liaoning 116034,China,2.Liaoning Entry-Exit Inspection and Quarantine Bureau,Liaoning 116001,China) |
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| Abstract: | A new high performance liquid chromatography/ultraviolet-visible detector(HPLC/UV-Vis) method was developed for the simultaneous determination of four forbidden colorants in cosmetics.The cosmetic sample was extracted using ethanol as solvent and the extract was analyzed by HPLC using a C18 reversed-phase column(5 μm,250 mm×4.6 mm) with gradient elution using acetonitrile(A) and 0.5% H3PO4(B) as mobile phase.The quantitative analysis was carried out by external standard method using UV-Vis as detector with detection wavelength at 530 nm.The LODs of Basic Violet 1,Pigment Orange 5,Sudan Blue 2 and Sudan Red IV were identified as 0.05,0.5,0.5,0.2 μg/mL respectively.The average recoveries of four colorants range from 86% to 100% with RSDs of 3.68%~8.02%. |
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| Keywords: | cosmetics additives HPLC colorants |
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