| 3，4-亚甲二氧基苯乙胺的合成新方法 |
| |
| 引用本文： | 黄红霞,林原斌.3，4-亚甲二氧基苯乙胺的合成新方法[J].精细与专用化学品,2007,15(12):11-13. |
| |
| 作者姓名： | 黄红霞 林原斌 |
| |
| 作者单位： | 1. 桂林工学院材料与化学工程系,广西,桂林,541004
2. 湘潭大学化学学院,湖南,湘潭,411105 |
| |
| 摘 要： | 以胡椒胺为原料,通过Sandmeyer反应制得3,4-亚甲二氧基溴苯(收率75.0%),再经Grignard反应(收率74.8%)、酯化反应(收率94.0%)和Gabriel反应(收率63.0%)制备出3,4-亚甲二氧基苯乙胺,并通过红外光谱和色谱-质谱联用确定了目标产物的结构。讨论温度对各步反应的影响,确定了最佳反应条件。
|
| 关 键 词： | 胡椒胺 3 4-亚甲二氧基苯乙胺 溴化亚铜 Gabriel反应 |
| 修稿时间： | 2007年3月13日 |
Novel Method for Synthesis of 3,4-Methylenedioxy Phenethylamine |
| |
| HUANG Hong-xia,LIN Yuan-bin.Novel Method for Synthesis of 3,4-Methylenedioxy Phenethylamine[J].Fine and Specialty Chemicals,2007,15(12):11-13. |
| |
| Authors: | HUANG Hong-xia LIN Yuan-bin |
| |
| Abstract: | Starting with 3,4-methylenedioxy aniline, the intermediate 3,4-methylenedioxy bromobenzene was obtained through Sandmeyer reaction (the yield was 75.0%), then the objective product 3,4-methylenedioxy phenethylamine was prepared with Grignard reaction (the yield was 74.8%), esterification (the yield was 94.0%) and Gabriel reaction (the yield was 63.0%). Finally the structure of product was characterized by IR spectrum and liquid chromatograph-mass spectrometer (LC-MS). The effects of temperature on the each reaction were discussed, and the optimum reaction condition was determined. |
| |
| Keywords: | 3 4-methylenedioxy aniline 3 4-methylenedioxy phenethylamine cuprous bromide Gabriel reaction |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
