| 通过通量平衡分析计算经验和真实维持系数 |
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| 引用本文： | 马红武,赵学明,郭晓峰.通过通量平衡分析计算经验和真实维持系数[J].中国化学工程学报,2002,10(1):89-92. |
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| 作者姓名： | 马红武 赵学明 郭晓峰 |
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| 作者单位： | SchoolofChemicalEngineering＆Technology,TianjinUniversity,Tianjin300072,China |
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| 基金项目： | Supported by the Key Program of National Natural Science Foundation of China (No. 20036010) and the National Science Fund for Distinguished Young Scholars (No. 20028607). |
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| 摘 要： | The stoichiometric matrix of a simplified metabolic network in Bacillus Subtillis was contructed from the flux balance equations, which were used for reconciliation of the measured rates and determination of the inner metabolic rates. Thus more reliable results of the true and empirical maintenance coefficients were obtained. The true maintenance coefficient is linearly related to the specific growth rate and changes with the P/O ratiol. The neasured biomass yield of adenosine triphosphate (ATP) is also linearly related to the P/O ratio.
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| 关 键 词： | 保持系数 发酵过程 代谢网络 |
| 修稿时间： | |
Calculation of Empirical and True Maintenance Coefficients by Flux Balance Analysis |
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| Ma Hongwu,Zhao Xueming,Guo Xiaofeng.Calculation of Empirical and True Maintenance Coefficients by Flux Balance Analysis[J].Chinese Journal of Chemical Engineering,2002,10(1):89-92. |
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| Authors: | Ma Hongwu Zhao Xueming Guo Xiaofeng |
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| Affiliation: | School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, China |
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| Abstract: | The stoichiometric matrix of a simplified metabolic network in Bacillus Subtillis was constructed from the flux balance equations, which were used for reconciliation of the measured rates and determination of the inner metabolic rates. Thus more reliable results of the true and empirical maintenance coefficients were obtained. The true maintenance coefficient is linearly related to the specific growth rate and changes with the P/O ratio. The measured biomass yield of adenosine triphosphate(ATP) is also linearly related to the P/O ratio. |
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| Keywords: | maintenance coefficient flux balance analysis metabolic network biomass yield |
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