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Investigation of the Metabolic Flux Analysis Method for Overdetermined System
作者姓名:马红武  郭晓峰  赵学明  鲁晋
作者单位:MA Hongwu GUO Xiaofeng(郭晓峰),ZHAO Xueming(赵学明) andLU JinDepartment of Bioengineering,School of Chemical Engineering & Technology,Tianjin University,Tianjin 300072,China
基金项目:Supported by the National Natural Science Foundation of China (No. 20036010), the National Science Fund for Distinguished Young Scholars (No. 20028607) and the Doctorate Foundation of MOE (No. 20000005622).
摘    要:With the xanthan synthesis in Xanthomonas campestris as an example, two methods for metabolic flux analysis of overdetermined system, the experimental data error minimization method and the equation error minimization method, are compared from their mathematical basis, rationality of the results and the easiness of computation. The results show that the experimental data error minimization method is appropriate in metabolic flux analysis of overdetermined system.


Investigation of the Metabolic Flux Analysis Method for Overdetermined System
MA Hongwu,GUO Xiaofeng.Investigation of the Metabolic Flux Analysis Method for Overdetermined System[J].Chinese Journal of Chemical Engineering,2002(2).
Authors:MA Hongwu  GUO Xiaofeng
Abstract:With the xanthan synthesis in Xanthomoaas campestris as an example, two methods for metabolic flux analysis of overdetermined system, the experimental data error minimization method and the equation error minimization method, are compared from their mathematical basis, rationality of the results and the easiness of computation. The results show that the experimental data error minimization method is appropriate in metabolic flux analysis of overdetermined system.
Keywords:metabolic flux analysis  overdetermined system  Xanthomonas campestris
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