| 磺化聚醚砜提高聚醚砜膜亲水性和血液相容性研究 |
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| 引用本文： | 王海涛,杨刘,赵学辉,于湉,杜启云.磺化聚醚砜提高聚醚砜膜亲水性和血液相容性研究[J].中国化学工程学报,2009,17(2):324-329. |
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| 作者姓名： | 王海涛 杨刘 赵学辉 于湉 杜启云 |
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| 作者单位： | 1. The Key Lab of Hollow Fiber Membrane Materials and Membrane Process of Ministry of Education, Tianjin Polytechnic University, Tianjin 300160, China;2. Department of Bio-medical Engineering, Tianjin Polytechnic University, Tianjin 300160, China |
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| 基金项目： | Supported by the Special Fund for International Cooperation Projects of China (2005DFA50160) |
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| 摘 要： | Polyethersulfone (PES) is widely used as biomaterials due to its thermal stability, mechanical strength, and chemical inertness. Nevertheless, their blood compatibility is still not adequate for hemodialysis and blood pu-rification. In this study, the sulfonated polyethersulfone (SPES) was synthesized through an electrophilic substitu-tion reaction, and PES/SPES blending membranes were prepared. The characterization of the SPES was studied by FTIR. The water adsorption and water contact angle experiments show that the hydrophilicity of PES/SPES blend membrane was improved as for the sulfonate group existing in the SPES. Moreover, PES/SPES blend membrane could effectively reduce bovine serum albumin adsorption and prolong the blood coagulation time compared with the PES membrane, thereby improving blood compatibility.
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| 关 键 词： | sulfonated polyethersulfone polyethersulfone hydrophilicity blood compatibility blending |
| 收稿时间： | 2008-8-28 |
| 修稿时间： | 2008-8-28
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Improvement of hydrophilicity and blood compatibility on polyethersuifone membrane by blending sulfonated polyethersulfone |
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| WANG Haitao,YANG Liu,ZHAO Xuehui,YU Tian,DU Qiyun.Improvement of hydrophilicity and blood compatibility on polyethersuifone membrane by blending sulfonated polyethersulfone[J].Chinese Journal of Chemical Engineering,2009,17(2):324-329. |
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| Authors: | WANG Haitao YANG Liu ZHAO Xuehui YU Tian DU Qiyun |
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| Affiliation: | 1. The Key Lab of Hollow Fiber Membrane Materials and Membrane Process of Ministry of Education, Tianjin Polytechnic University, Tianjin 300160, China;2. Department of Bio-medical Engineering, Tianjin Polytechnic University, Tianjin 300160, China |
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| Abstract: | Polyethersulfone (PES) is widely used as biomaterials due to its thermal stability, mechanical strength, and chemical inertness. Nevertheless, their blood compatibility is still not adequate for hemodialysis and blood pu-rification. In this study, the sulfonated polyethersulfone (SPES) was synthesized through an electrophilic substitu-tion reaction, and PES/SPES blending membranes were prepared. The characterization of the SPES was studied by FTIR. The water adsorption and water contact angle experiments show that the hydrophilicity of PES/SPES blend membrane was improved as for the sulfonate group existing in the SPES. Moreover, PES/SPES blend membrane could effectively reduce bovine serum albumin adsorption and prolong the blood coagulation time compared with the PES membrane, thereby improving blood compatibility. |
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| Keywords: | sulfonated polyethersulfone polyethersulfone hydrophilicity blood compatibility blending |
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