| 卷烟主流烟气中烟草特有亚硝胺的测定 |
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| 引用本文： | 张凤梅,杨柳,孟昭宇,吴亿勤,伊奥尔,牟定荣.卷烟主流烟气中烟草特有亚硝胺的测定[J].化学与生物工程,2012(3):92-94. |
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| 作者姓名： | 张凤梅 杨柳 孟昭宇 吴亿勤 伊奥尔 牟定荣 |
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| 作者单位： | 红塔烟草(集团)有限责任公司技术中心 |
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| 摘 要： | 建立了一种高效液相色谱-串联质谱联用法测定卷烟主流烟气中烟草特有亚硝胺的方法。采用含10ng.mL-1内标的0.1mol.L-1乙酸铵溶液直接对收集了主流烟气的剑桥滤片进行超声萃取30min,过膜后的萃取液用带电喷雾装置的LC-MS/MS仪进行分析。该方法数据可靠、操作简单、重复性好。
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| 关 键 词： | 烟草特有亚硝胺 卷烟主流烟气 高效液相色谱 串联质谱 |
Determination of Tobacco-Specific N-Nitrosamines in Mainstream Cigarette Smoke |
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| ZHANG Feng-mei,YANG Liu,MENG Zhao-yu,WU Yi-qin,Yi Ao-er,MOU Ding-rong.Determination of Tobacco-Specific N-Nitrosamines in Mainstream Cigarette Smoke[J].Chemistry & Bioengineering,2012(3):92-94. |
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| Authors: | ZHANG Feng-mei YANG Liu MENG Zhao-yu WU Yi-qin Yi Ao-er MOU Ding-rong |
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| Affiliation: | (R&D Center of Hongta Tobacco Group Co.,Ltd.,Yuxi 653100,China) |
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| Abstract: | A high performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS) method for determining four tobacco-specific N-nitrosamines(TSNAs) in mainstream cigarette smoke was established.Mainstream cigarette smoke particulate matter was collected on a Cambridge filter pad,further extracted using 0.1 mol·L-1 ammonium acetate with 10 ng ·L-1 internal standard addition,and subsequently analyzed with HPLC-MS/MS.The proposed method was proved to be accurate,simple and repeatable. |
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| Keywords: | tobacco-specific N-nitrosamine mainstream cigarette smoke high performance liquid chromatography tandem mass spectrometry |
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