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药物释放系统
引用本文:刘袖洞,马小军,袁权.药物释放系统[J].化工学报,2005,56(6):955-961.
作者姓名:刘袖洞  马小军  袁权
作者单位:中国科学院大连化学物理研究所,辽宁 大连 116023
基金项目:国家自然科学基金项目(20176056,50373046).~~
摘    要:介绍了口服、透皮、黏膜等非注射给药途径药物释放系统的研究进展,以及靶向、细胞微囊化和微加工等新技术手段在药物释放系统中的应用,评述了药物释放系统的问题及解决手段.

关 键 词:药物释放系统  靶向  细胞微囊化  微加工  
文章编号:0438-1157(2005)06-0955-07
收稿时间:2004-11-8
修稿时间:2005-4-13  

Drug delivery systems
LIU Xiudong,Ma Xiaojun,YUAN Quan.Drug delivery systems[J].Journal of Chemical Industry and Engineering(China),2005,56(6):955-961.
Authors:LIU Xiudong  Ma Xiaojun  YUAN Quan
Abstract:Drug delivery systems (DDS) have been developed as a new means of releasing drugs with accurate dosage and convenient administration.It will be promising in clinical application with high effectiveness and safety of drugs, and high compliance of patients.In this review, the status quo and progress of main non-injection routes (oral,trans-dermal and mucosal DDS) are summarized.The application of novel technologies such as targeting, cell micro-encapsulation and micro-fabrication in DDS is introduced.Finally, the problems and some strategy to resolve such problems are addressed.
Keywords:drug delivery systems  targeting  cell micro-encapsulation  micro-fabrication  
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