| 2-氯丙酸异丙酯的合成 |
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| 引用本文： | 李勇,田青松,张文静,王玉东.2-氯丙酸异丙酯的合成[J].河北化工,2012(9):45-46,49. |
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| 作者姓名： | 李勇 田青松 张文静 王玉东 |
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| 作者单位： | 河北万全宏宇化工有限责任公司 |
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| 摘 要： | 以固体超强酸树脂为催化剂合成2-氯丙酸异丙酯,研究了催化剂的用量、反应起始原料物质的量比、反应时间、带水剂种类及用量对酯化反应的影响,确定了合成2-氯丙酸异丙酯的最佳反应条件为:n(异丙醇)∶n(环己烷)∶n(催化剂)∶n(2-氯丙酸)=5∶6.5∶0.3∶1,反应时间为2h,在此条件下,2-氯丙酸异丙酯的收率可达到95%,纯度达到99%以上。
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| 关 键 词： | 2-氯丙酸 2-氯丙酸异丙酯 合成 |
Synthesis of Isopropyl 2-chloropropionate |
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| LI Yong,TIAN Qing-song,ZHANG Wen-jing,WANG Yu-dong.Synthesis of Isopropyl 2-chloropropionate[J].Hebei Chemical Engineering and Industry,2012(9):45-46,49. |
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| Authors: | LI Yong TIAN Qing-song ZHANG Wen-jing WANG Yu-dong |
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| Affiliation: | (Hebei Wanquan Hongyu Chemical Co.,Ltd,Zhangjiakou 076271,China) |
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| Abstract: | To synthesize isopropyl 2-chloropropionate with super acid resin as catalyst,and study the influences of catalyst dosage,raw material ratio,reaction time water-carrying agent varieties and dosage.The total yield was 95% and purity of the title compound was above 99% under the optimum conditions that included n(2-propanol)∶n(cyclohexane)∶n(catalyst)∶n(2-chloropropionic acid)=5∶6.5∶0.3∶1,and reaction time was 2 h. |
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| Keywords: | 2-chloropropionic acid isopropyl 2-chloropropionate synthesis |
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