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| 黄柏化学成分研究 | |
| 引用本文： | 李行诺,翟文丰,周孟宇,沈培强,葛志伟,颜继忠.黄柏化学成分研究[J].浙江工业大学学报,2012,40(3):244-246. |
| 作者姓名： | 李行诺 翟文丰 周孟宇 沈培强 葛志伟 颜继忠 |
| 作者单位： | 1. 浙江工业大学 药学院,浙江杭州,310032 2. 正大青春宝药业有限公司,浙江杭州,310023 3. 浙江大学 药学院,浙江杭州,310058 |
| 基金项目： | 国家重大科技专项项目(2009ZX09313-036) |
| 摘 要： | 对黄柏树皮Phellodendron chinese Schneid的化学成分进行研究,从中寻找有重要生物活性及药用前景的天然化合物.采用硅胶柱色谱法结合制备高效液相进行分离和纯化,根据理化性质和波谱数据进行结构鉴定.从黄柏树皮的乙醇提取物中分离得到6个化合物,分别为异阔果芸香碱(Ⅰ),γ-花椒碱(Ⅱ),茵芋碱(Ⅲ),铁屎米酮(Ⅳ),阿魏酸(Ⅳ),5-O-阿魏酰基奎宁酸(Ⅵ).化合物Ⅰ为首次从该属植物中分离得到. |
| 关 键 词： | 黄柏 化学成分 生物碱 |
Chemical constituents from Phellodendron chinese |
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| LI Xing-nuo , ZHAI Wen-feng , ZHOU Meng-yu , SHEN Pei-qiang , GE Zhi-wei , YAN Ji-zhong.Chemical constituents from Phellodendron chinese[J].Journal of Zhejiang University of Technology,2012,40(3):244-246. | |
| Authors: | LI Xing-nuo ZHAI Wen-feng ZHOU Meng-yu SHEN Pei-qiang GE Zhi-wei YAN Ji-zhong |
| Affiliation: | 1(1.College of Pharmaceutical Science,Zhejiang University of Technology,Hangzhou 310032,China; 2.Chiatai Qingchunbao Pharmacentical Co.,Ltd.,Hangzhou 310023,China; 3.Pharmaceutical Informatics Institute,Zhejiang University,Hangzhou 310058,China) |
| Abstract: | To search for bioactive natural products,the chemical constituents of Phellodendron chinese were studied.The compounds Ⅰ-Ⅵ were isolated by various chromatographic methods and their structures were identified by spectroscopic analysis.Six compounds were isolated from the ethanol etracts of Phellodendri chinensis Cortex.isoplatydesmine(Ⅰ),γ-fagarine(Ⅱ),skimmianine(Ⅲ),canthin-6-one(Ⅳ),ferulic acid(Ⅴ),5-O-feruloylquinic acids(Ⅵ).Compound I was isolated from the Phellodendron genus for the first time. |
| Keywords: | Phellodendron chinese chemical constituents alkaloid |
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