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无机纳米催化剂在化学动力学疗法的研究进展
引用本文:白鑫,张旻昳,郑喃喃,王金霞,赵行,管少琪,王星妍,陆杰,刘锡建.无机纳米催化剂在化学动力学疗法的研究进展[J].上海工程技术大学学报,2020,34(4):324-330.
作者姓名:白鑫  张旻昳  郑喃喃  王金霞  赵行  管少琪  王星妍  陆杰  刘锡建
作者单位:上海工程技术大学化学化工学院,上海201620
摘    要:化学动力学疗法(CDT)是一种侵袭性小的新兴肿瘤治疗方式. 其通过将纳米催化剂引入肿瘤治疗中,促进肿瘤内产生特定毒性的活性氧,从而杀死肿瘤细胞. 从化学动力疗法的原理,无机纳米催化材料的选择,CDT协同光热治疗、化疗、光动力学治疗、放疗共同提升肿瘤治疗效率这几个方面进行综述,说明CDT有望成为一种新型的替代性的肿瘤治疗方式.

关 键 词:化学动力学疗法(CDT)  纳米催化剂  协同治疗  芬顿反应
收稿时间:2020-08-07

Research Progress of Inorganic Nano-Catalyst for Chemodynamic Therapy
BAI Xin,ZHANG Mingyi,ZHENG Nannan,WANG Jinxia,ZHAO Hang,GUAN Shaoqi,WANG Xingyan,LU Jie,LIU Xijian.Research Progress of Inorganic Nano-Catalyst for Chemodynamic Therapy[J].Journal of Shanghai University of Engineering Science,2020,34(4):324-330.
Authors:BAI Xin  ZHANG Mingyi  ZHENG Nannan  WANG Jinxia  ZHAO Hang  GUAN Shaoqi  WANG Xingyan  LU Jie  LIU Xijian
Affiliation:School of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, Shanghai 201620, China
Abstract:Chemodynamic therapy (CDT) is a minimally aggressive emerging cancer treatment, which introduces nanocatalysts into cancer treatment to promote the production of specific toxic reactive oxygen species (ROS) in tumors, inducing the death of tumor cells. Summaried from the aspects of the mechanism of CDT, the choice of nanocatalytic materials, and combinations of CDT with photothermal therapy, chemotherapy, photodynamic therapy and radiotherapy to improve the efficiency of tumor treatment, it indicates that the CDT is expected to become an alternative method of tumor treatment.
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