Zn^2+ Release Performance in Simulated Uterine Solution and Surface Characteristics of ZnO/LDPE Nanocomposites |
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作者姓名: | YANG Zhihong XIE Changsheng |
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作者单位: | [1]State Key Laboratory of Plastic Forming Simulation and Mould Technology, Deparment of Material Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China [2]Faculty of material science and chemical engineering, China University of geosciences, Wuhan 430074, China |
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基金项目: | Funded by the National Natural Science Foundation of China (No.50271029 and 50041024), the Ten-fifth Project of Ministry of Science and Technology (No. 2004BA709B14-01 ), the Natural Science Foundation of China University of Geosciences (No. CUGQNL0521 ) |
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摘 要: | Zinc oxide/low-density polyethylene (LDPE) nanocomposites were prepared for intrauterine devices. The change of Zn^2+ release rates of nanocomposites ( doped with various mass fractions of zinc oxide nanoparticles between 5wt% and 65 wt% ) for 264 days in a simulated uterine solution were investigated. The resuits show that initial burst phases are followed by near zero-order release phases. SEM technique was employed to observe the surface morphology of the 45wt% ZnO/ LDPE composite. Elements and phases on the surface of the nanocomposite after incubation were also analyzed by EDX and XRD respectively. The experimental results show that incrustation formation does not occur after incubation.
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关 键 词: | 氧化锌/低密度聚乙烯纳米复合物 锌离子释放速度 表面特性 宫内避孕器 |
收稿时间: | 2005-03-14 |
修稿时间: | 2005-09-16 |
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