| 药用级凹凸棒黏土质量指标的初步研究 |
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| 引用本文： | 马旭伟,张明,吴洁.药用级凹凸棒黏土质量指标的初步研究[J].淮阴工学院学报,2013(3):11-15. |
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| 作者姓名： | 马旭伟 张明 吴洁 |
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| 作者单位： | 淮阴工学院生命科学与化学工程学院;江苏省凹土资源利用重点实验室 |
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| 基金项目： | 江苏省教育厅高校科研成果产业化推进项目(JHB2012-57);淮安市“533英才工程”资助项目;江苏省高等学校大学生实践创新训练计划项目(12040) |
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| 摘 要： | 研究药用级凹凸棒黏土的质量标准。分析比较美国药典(USP)、英国药典(BP)和我国卫生部标准(MOH)中凹凸棒黏土的质量指标,按照美国药典规定的方法,用红外光谱(FT-IR)和X-射线衍射(XRD)对经自然沉降法纯化处理的盱眙凹土进行鉴别,并对其重金属含量、微生物限度、pH值、失重、粉末细度等指标进行检测。检测结果符合药典规定,检测方法简单易行,可用于药用级凹凸棒黏土质量的控制。
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| 关 键 词： | 凹凸棒黏土 药用级 质量标准 |
A Pilot Study on the Quality Index of Pharmaceutical Grade Attapulgite |
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| MA Xu-wei,ZHANG Ming,WU Jie.A Pilot Study on the Quality Index of Pharmaceutical Grade Attapulgite[J].Journal of Huaiyin Institute of Technology,2013(3):11-15. |
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| Authors: | MA Xu-wei ZHANG Ming WU Jie |
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| Affiliation: | 1,2(1.Faculty of Life Science & Chemical Engineering,Huaiyin Institute of Technology,Huai’an Jiangsu 223003,China;2.Attapulgite Resource Utilization Key Laboratory of Jiangsu Province,Huai’an Jiangsu 223003,China) |
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| Abstract: | The quality index of pharmaceutical grade attapulgite was studied in this paper. To establish quality standards for pharmaceutical grade attapulgite in China, the quality index of attapulgite recorded in United States pharmacopoeia （USP） standards, British pharmacopoeia （ BP） standards and Chinag ministry of health （MOH） standards were compared and analyzed. In accordance with the methods described in USP, Xuyi Attapulgite, which was purified with natural sedimentation, was differentiated by means of fourier transform infra- red spectroscopy （ FT - IR） and X - ray diffraction （ XRD ）. The quality indexes of Xuyi Attapulgite, such as the content of heavy metal, microbial limit, pH value, weight loss and fineness of attapulgite clay, were examined. The result shows that the quality of attapulgite meets the requirement of USP. The detection methods are simple and practicable, and they can be used in the quality control of pharmaceutical grade attapulgite. |
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| Keywords: | attapulgite pharmaceutical grade quality index |
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