| 广西甜橙皮黄酮类等化学成分的研究 |
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| 引用本文： | 翟福东 张淑芬. 广西甜橙皮黄酮类等化学成分的研究[J]. 北京工业大学学报, 1997, 23(1): 39-43 |
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| 作者姓名： | 翟福东 张淑芬 |
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| 作者单位： | 北京工业大学化学与环境工程学系 |
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| 摘 要： | 对广西甜橙皮中的黄酮类等化学成分进行了分离和鉴定。从中性乙醚提取物中分离得到５种结晶成分，经理化性质的测定及光谱分析，有３种物质鉴定为甲氧基取代的黄酮类化合物，分别为３，５，６，７，８，３＇，４＇，－七甲氧基黄酮（Ⅰ）；蜜桔素（Ⅱ）和川陈皮素（Ⅲ），另２种物质分别鉴定为β－谷甾醇（Ⅳ）和木栓酮（Ⅴ）．其中化合物Ⅰ和Ⅴ均是首次从国内柑桔果皮中分离得到，化合物Ⅰ的体外细胞抑瘤实验已初步表明，它对人体白血病细胞（Ｋ５６２）有很明显的抑制作用。
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| 关 键 词： | 甜橙皮，聚甲氧基黄酮化合物，3，5，6，7，8，3＇，4＇－七甲氧基黄酮 |
Study on the Constituents of the Flavonoids and Other Substances From the Peel of Citrus Sinensis (L.) Osbeck |
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| Zhai Fudong Zhang Shufen Wang Xiaoyi Ma Binglun Dai Qianhuan. Study on the Constituents of the Flavonoids and Other Substances From the Peel of Citrus Sinensis (L.) Osbeck[J]. Journal of Beijing Polytechnic University, 1997, 23(1): 39-43 |
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| Authors: | Zhai Fudong Zhang Shufen Wang Xiaoyi Ma Binglun Dai Qianhuan |
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| Abstract: | Five compounds in the crystal form were isolated from dry peel of citrus Sinensis(L.)Osbeck collected from GuangXi province. By means of physico-chemical evidence andspectroscopic analysis( UV, IR, MS, 1HNMR), three components were characterized as poly-methoxyflavonoids. They were 3, 5, 6, 7, 8, 3', 4'-heptamethoxy flavone (I), tangeretin (II) andnobiletin (III).B-sitosterol (IV) and friedelin( V ), which were also identified. Among them, 3, 5, 6, 7,8, 3', 4'-heptamethoxy flavone and friedelin were first obtained from domestic citrus peels. Heptamethoxy flavone was found having significant inhibitory action in the experiment with human Leukemic cell ( K 562). |
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| Keywords: | citrussinensis (L.) osbeck peel polymethoxy-flavonoids 3 5 6 7 8 3' 4'-heptamethoxyflavone |
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