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Dynamically modulated intensity interrogation scheme using waveguide coupled surface plasmon resonance sensors
Authors:Xin Ma  Xinlong Xu  Zheng Zheng  Kun Wang  Yalin Su  Jiangfeng Fan  Rui Zhang  Lusheng Song  Zhiyou Wang  Jinsong Zhu
Affiliation:1. National Center for NanoScience and Technology, No. 11 Beiyitiao, Zhongguancun, Beijing 100190, China;2. School of Electronic and Information Engineering, Beihang University, 37 Xueyuan Rd., Beijing 100191, China
Abstract:An electro-optically modulated intensity interrogation method based on tunable waveguide coupled surface plasmon resonance sensors has been proposed. It has been theoretically and experimentally demonstrated that the proposed scheme can enable sensitive measurement of measurand variations. By modulating the refractive index in the waveguide layer, this interrogation method yields modulated signal whose amplitude is related to measurand's refractive index. This amplitude modulated signal offers a higher signal to noise ratio and eliminates additive noise in the sensor system. A preliminary investigation using saline buffers with different NaCl concentrations shows a resolution of 2.3 × 10?6 refractive index unit by our approach. Resolution can be controlled by the amplitude of the applied modulation voltage and can be further enhanced by optimizing the device structure or improving the electro-optical (E-O) coefficient of the E-O material. This approach is simple, stable, and promising for low-cost or multi-channel SPR biosensor applications.
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