肺癌呼吸气体检测系统的气室设计

基于卟啉传感器阵列(PSA)的肺癌呼吸气体检测系统是通过采集处理PSA芯片表面图谱信息来对人体呼吸气体进行定性检测,达到早期肺癌诊断的目的。检测过程中,PSA芯片能否与气体分子快速、均匀结合将直接影响气体检测系统的准确度。以系统中PSA芯片与肺癌呼吸气体反应的气室为研究对象,借助CFD专用软件FLUENT对气室进行流场仿真结构优化,在气室理论模型的基础上,进行了气室实物制作,结果表明:通过采用抛物线形气室内腔、安装导流板、减小分流孔通径、适当加大分流孔倾斜角度等优化方案后,气室内呼吸气体呈层流流动状态,流场更加均匀、密集,能达到检测系统中PSA芯片与呼吸气体分子快速、均匀结合的要求。

Design of gas chamber of lung cancer respiratory gas detection system

Lung cancer respiratory gas detection system based on Porphyrin sensor arrays(PSAs)is used to detect human respiratory gases qualitatively through the acquisition and processing the information of PSA images,to achieve the purpose of early lung cancer diagnosis.In the detection process,whether PSA chips can bind gas molecules rapidly and uniformly,directly affects the accuracy of detection system.The chamber in which PSA chips reacts with lung cancer respiratory gases as the research object,is produced physically on the basis of the gas theoretical model with FLUENT which is a kind of CFD special software,simulating the gas chamber flow filed and optimizing its structure.The results show that the gas chamber using the optimization options of parabolic chamber cavity,installation of guide plates,reducing the diameter of diversion holes and increasing the tilt angle of diversion holes appropriately,in which the respiratory gases show a laminar flow state and the flow field is more uniform and dense,can achieve the requirements of PSA chips binding with gas molecules rapidly and uniformly.