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Semiautomatic leakage analyzing system for time series fluorescein ocular fundus angiography
Authors:Shinichi Tamura  Kokichi Tanaka  Seiji Ohmori  Kozo Okazaki  Akira Okada  Mitsuru Hoshi
Affiliation:1. Department of Information and Computer Sciences, Faculty of Engineering Science, Osaka University, Toyonaka, Osaka 560, Japan;2. Department of Internal Medicine, Osaka Police Hospital, Tennoji-ku, Osaka 543, Japan;3. Department of Electrical Engineering, Faculty of Engineering, Tottori University, Tottori, Tottori 680, Japan;4. The First Department of Medicine, Osaka University Medical School, Fukushima-ku, Osaka 553, Japan;5. Department of Medicine, Osaka Kosei-Nenkin Hospital, Fukushima-ku, Osaka 553, Japan
Abstract:An algorithm for measuring an index of leakage in fluorescein fundus angiography is presented. The number of pixels whose gray level exceeds an automatically determined slice level is calculated. An automatic blood vessel elimination technique is introduced. Further, a method of measuring the short term change of leakage from a time series of the fluorescein fundus angiographs is described. Our system can also deal with the time series images obtained on different occasions (long term change).The features of this paper are: (1) this paper deals with double time sequence images (short and long term); (2) an automatic blood vessel recognition algorithm is employed.
Keywords:Image processing  Pattern recognition  Time series images  Blood vessel elimination  Ocular fundus photograph  Diabetic retinopathy  Fluorescein fundus angiography
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